| EC |
2.7.3.9 |
| Accepted name: |
phosphoenolpyruvate—protein phosphotransferase |
| Reaction: |
phosphoenolpyruvate + protein histidine = pyruvate + protein Nπ-phospho-L-histidine |
| Other name(s): |
phosphoenolpyruvate sugar phosphotransferase enzyme I; phosphopyruvate-protein factor phosphotransferase; phosphopyruvate-protein phosphotransferase; sugar-PEP phosphotransferase enzyme I; phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase |
| Systematic name: |
phosphoenolpyruvate:protein-L-histidine Nπ-phosphotransferase |
| Comments: |
Enzyme I of the phosphotransferase system (cf. EC 2.7.1.69 protein-Nπ-phosphohistidine—sugar phosphotransferase). Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport. A similar reaction, where the protein is the enzyme EC 2.7.9.2 pyruvate, water dikinase, is part of the mechanism of that enzyme. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37278-17-4 |
| References: |
| 1. |
Postma, P.W. and Roseman, S. The bacterial phosphoenolpyruvate: sugar phosphotransferase system. Biochim. Biophys. Acta 457 (1976) 213–257. [PMID: 187249] |
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| [EC 2.7.3.9 created 1972] |
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