| EC |
2.7.4.2 |
| Accepted name: |
phosphomevalonate kinase |
| Reaction: |
ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate |
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For diagram of terpenoid biosynthesis, click here |
| Other name(s): |
ATP:5-phosphomevalonate phosphotransferase; 5-phosphomevalonate kinase; mevalonate phosphate kinase; mevalonate-5-phosphate kinase; mevalonic acid phosphate kinase |
| Systematic name: |
ATP:(R)-5-phosphomevalonate phosphotransferase |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9026-46-4 |
| References: |
| 1. |
Bloch, K., Chaykin, S., Phillips, A.H. and de Waard, A. Mevalonic acid pyrophosphate and isopentenyl pyrophosphate. J. Biol. Chem. 234 (1959) 2595–2604. [PMID: 13801508] |
| 2. |
Henning, U., Möslein, E.M. and Lynen, F. Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase. Arch. Biochem. Biophys. 83 (1959) 259–267. [DOI] [PMID: 13662013] |
| 3. |
Levy, G.B. and Popják, G. Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver. Biochem. J. 75 (1960) 417–428. [PMID: 14416398] |
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| [EC 2.7.4.2 created 1961] |
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