EC |
2.7.4.6 |
Accepted name: |
nucleoside-diphosphate kinase |
Reaction: |
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate |
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For diagram of GTP biosynthesis, click here |
Other name(s): |
nucleoside 5′-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridine diphosphate kinase |
Systematic name: |
ATP:nucleoside-diphosphate phosphotransferase |
Comments: |
Many nucleoside diphosphates can act as acceptors, while many ribo- and deoxyribonucleoside triphosphates can act as donors. |
Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9026-51-1 |
References: |
1. |
Berg, P. and Joklik, W.K. Enzymatic phosphorylation of nucleoside diphosphates. J. Biol. Chem. 210 (1954) 657–672. [PMID: 13211603] |
2. |
Gibson, D.M., Ayengar, P. and Sanadi, D.R. Transphosphorylations between nucleoside phosphates. Biochim. Biophys. Acta 21 (1956) 86–91. [DOI] [PMID: 13363863] |
3. |
Kirkland, R.J.A. and Turner, J.F. Nucleoside diphosphokinase of pea seeds. Biochem. J. 72 (1959) 716–720. [PMID: 14409347] |
4. |
Krebs, H.A. and Hems, R. Some reactions of adenosine and inosine phosphates in animal tissues. Biochim. Biophys. Acta 12 (1953) 172–180. [DOI] [PMID: 13115426] |
5. |
Nakamura, H. and Sugino, Y. Metabolism of deoxyribonucleotides. 3. Purification and some properties of nucleoside diphosphokinase of calf thymus. J. Biol. Chem. 241 (1966) 4917–4922. [PMID: 5925862] |
6. |
Ratliff, R.L., Weaver, R.H., Lardy, H.A. and Kuby, S.A. Nucleoside triphosphate-nucleoside diphosphate transphosphorylase (nucleoside diphosphokinase). I. Isolation of the crystalline enzyme from brewers' yeast. J. Biol. Chem. 239 (1964) 301–309. [PMID: 14114857] |
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[EC 2.7.4.6 created 1961] |
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