| EC |
2.7.4.7 |
| Accepted name: |
phosphooxymethylpyrimidine kinase |
| Reaction: |
ATP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine = ADP + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine |
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For diagram of thiamine diphosphate biosynthesis, click here |
| Glossary: |
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine = (4-amino-2-methylpyrimidin-5-yl)methyl dihydrogen phosphate |
| Other name(s): |
hydroxymethylpyrimidine phosphokinase; ATP:4-amino-2-methyl-5-phosphooxymethylpyrimidine phosphotransferase; ATP:(4-amino-2-methylpyrimidin-5-yl)methyl-phosphate phosphotransferase; phosphomethylpyrimidine kinase |
| Systematic name: |
ATP:4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine phosphotransferase |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37278-18-5 |
| References: |
| 1. |
Lewin, L.M. and Brown, G.M. The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine. J. Biol. Chem. 236 (1961) 2768–2771. |
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| [EC 2.7.4.7 created 1965, modified 2016] |
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