The Enzyme Database

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Accepted name: GTP diphosphokinase
Reaction: ATP + GTP = AMP + guanosine 3′-diphosphate 5′-triphosphate
Other name(s): stringent factor; guanosine 3′,5′-polyphosphate synthase; GTP pyrophosphokinase; ATP-GTP 3′-diphosphotransferase; guanosine 5′,3′-polyphosphate synthetase; (p)ppGpp synthetase I; (p)ppGpp synthetase II; guanosine pentaphosphate synthetase; GPSI; GPSII
Systematic name: ATP:GTP 3′-diphosphotransferase
Comments: GDP can also act as acceptor.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 63690-89-1
1.  Fehr, S. and Richter, D. Stringent response of Bacillus stearothermophilus: evidence for the existence of two distinct guanosine 3′,5′-polyphosphate synthetases. J. Bacteriol. 145 (1981) 68–73. [PMID: 6161916]
2.  Sy, J. and Akers, H. Purification and properties of guanosine 5′,3′-polyphosphate synthetase from Bacillus brevis. Biochemistry 15 (1976) 4399–4403. [PMID: 184817]
[EC created 1981]

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