EC |
2.7.7.43 |
Accepted name: |
N-acylneuraminate cytidylyltransferase |
Reaction: |
CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate |
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For diagram of N-Acetylneuraminic acid biosynthesis, click here |
Other name(s): |
CMP-sialate pyrophosphorylase; CMP-sialate synthase; cytidine 5′-monophosphosialic acid synthetase; CMP-Neu5Ac synthetase; CMP-NeuAc synthetase; acylneuraminate cytidyltransferase; CMP-N-acetylneuraminate synthetase; CMP-N-acetylneuraminate synthase; CMP-N-acetylneuraminic acid synthase; CMP-NANA synthetase; CMP-sialate synthetase; CMP-sialic synthetase; cytidine 5′-monophospho-N-acetylneuraminic acid synthetase; cytidine 5-monophosphate N-acetylneuraminic acid synthetase; cytidine monophosphosialic acid synthetase; cytidine monophosphoacetylneuraminic synthetase; cytidine monophosphosialate pyrophosphorylase; cytidine monophosphosialate synthetase; acetylneuraminate cytidylyltransferase |
Systematic name: |
CTP:N-acylneuraminate cytidylyltransferase |
Comments: |
Acts on N-acetyl- and N-glycolyl- derivatives. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9067-82-7 |
References: |
1. |
Kean, E.L. and Roseman, S. The sialic acids. X. Purification and properties of cytidine 5′-monophosphosialic acid synthetase. J. Biol. Chem. 241 (1966) 5643–5650. [PMID: 4288894] |
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[EC 2.7.7.43 created 1972] |
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