| EC |
2.7.7.71 |
| Accepted name: |
D-glycero-α-D-manno-heptose 1-phosphate guanylyltransferase |
| Reaction: |
D-glycero-α-D-manno-heptose 1-phosphate + GTP = GDP-D-glycero-α-D-manno-heptose + diphosphate |
| Other name(s): |
hddC (gene name); gmhD (gene name) |
| Systematic name: |
GTP:D-glycero-α-D-manno-heptose 1-phosphate guanylyltransferase |
| Comments: |
The enzyme is involved in biosynthesis of GDP-D-glycero-α-D-manno-heptose, which is required for assembly of S-layer glycoprotein in some Gram-positive bacteria. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Kneidinger, B., Graninger, M., Puchberger, M., Kosma, P. and Messner, P. Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose. J. Biol. Chem. 276 (2001) 20935–20944. [DOI] [PMID: 11279237] |
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| [EC 2.7.7.71 created 2010] |
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