| EC |
2.7.7.9 |
| Accepted name: |
UTP—glucose-1-phosphate uridylyltransferase |
| Reaction: |
UTP + α-D-glucose 1-phosphate = diphosphate + UDP-glucose |
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For diagram of the biosynthesis of UDP-glucose, UDP-galactose and UDP-glucuronate, click here |
| Other name(s): |
UDP glucose pyrophosphorylase; glucose-1-phosphate uridylyltransferase; UDPG phosphorylase; UDPG pyrophosphorylase; uridine 5′-diphosphoglucose pyrophosphorylase; uridine diphosphoglucose pyrophosphorylase; uridine diphosphate-D-glucose pyrophosphorylase; uridine-diphosphate glucose pyrophosphorylase |
| Systematic name: |
UTP:α-D-glucose-1-phosphate uridylyltransferase |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9026-22-6 |
| References: |
| 1. |
Kalckar, H.M. The role of phosphoglycosyl compounds in the biosynthesis of nucleosides and nucleotides. Biochim. Biophys. Acta 12 (1953) 250–264. [DOI] [PMID: 13115434] |
| 2. |
Kamogawa, A. and Kurahashi, K. Purification and properties of uridinediphosphate glucose pyrophosphorylase from Escherichia coli K12. J. Biochem. (Tokyo) 57 (1965) 758–765. [PMID: 4284510] |
| 3. |
Lobelle-Rich, P.A. and Reeves, R.E. Separation and characterization of two UTP-utilizing hexose phosphate uridylyltransferases from Entamoeba histolytica. Mol. Biochem. Parasitol. 7 (1983) 173–182. [DOI] [PMID: 6304512] |
| 4. |
Smith, E.E.B. and Mills, G.T. The uridyl transferase of mammary gland. Biochim. Biophys. Acta 18 (1955) 152. [DOI] [PMID: 13260264] |
| 5. |
Turnquist, R.L., Gillett, T.A. and Hansen, R.G. Uridine diphosphate glucose pyrophosphorylase. Crystallization and properties of the enzyme from rabbit liver and species comparisons. J. Biol. Chem. 249 (1974) 7695–7700. [PMID: 4436332] |
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| [EC 2.7.7.9 created 1961] |
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