| EC |
2.7.8.11 |
| Accepted name: |
CDP-diacylglycerol—inositol 3-phosphatidyltransferase |
| Reaction: |
CDP-diacylglycerol + myo-inositol = CMP + 1-phosphatidyl-1D-myo-inositol |
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For diagram of 1-phosphatidyl-myo-inositol metabolism, click here |
| Glossary: |
1-phosphatidyl-1D-myo-inositol = PtdIns |
| Other name(s): |
CDP-diglyceride-inositol phosphatidyltransferase; phosphatidylinositol synthase; CDP-diacylglycerol-inositol phosphatidyltransferase; CDP-diglyceride:inositol transferase; cytidine 5′-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase; CDP-DG:inositol transferase; cytidine diphosphodiglyceride-inositol phosphatidyltransferase; CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase; CDP-diglyceride-inositol transferase; cytidine diphosphoglyceride-inositol phosphatidyltransferase; cytidine diphosphoglyceride-inositol transferase |
| Systematic name: |
CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9027-01-4 |
| References: |
| 1. |
Bleasdale, J.E., Wallis, P., MacDonald, P.C. and Johnston, J.M. Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue. Biochim. Biophys. Acta 575 (1979) 135–147. [DOI] [PMID: 41587] |
| 2. |
Prottey, C. and Hawthorne, J.N. The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas. Biochem. J. 105 (1967) 379–392. [PMID: 4293959] |
| 3. |
Salway, J.G., Harewood, J.L., Kai, M., White, G.L. and Hawthorne, J.N. Enzymes of phosphoinositide metabolism during rat brain development. J. Neurochem. 15 (1968) 221–226. [DOI] [PMID: 4295616] |
| 4. |
Takenawa, T. and Egawa, K. CDP-diglyceride:inositol transferase from rat liver. Purification and properties. J. Biol. Chem. 252 (1977) 5419–5423. [PMID: 18462] |
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| [EC 2.7.8.11 created 1972, modified 1976] |
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