ExplorEnz: EC 2.7.9.2

2.7.9.2

Accepted name:

pyruvate, water dikinase

Reaction:

ATP + pyruvate + H₂O = AMP + phosphoenolpyruvate + phosphate

Other name(s):

phosphoenolpyruvate synthase; pyruvate-water dikinase (phosphorylating); PEP synthetase; phosphoenolpyruvate synthase; phoephoenolpyruvate synthetase; phosphoenolpyruvic synthase; phosphopyruvate synthetase

Systematic name:

ATP:pyruvate, water phosphotransferase

Comments:

A manganese protein.

References:

1.	Berman, K.M. and Cohn, M. Phosphoenolpyruvate synthetase of Escherichia coli. Purification, some properties, and the role of divalent metal ions. J. Biol. Chem. 245 (1970) 5309–5318. [PMID: 4319237]
2.	Berman, K.M. and Cohn, M. Phosphoenolpyruvate synthetase. Partial reactions studied with adenosine triphosphate analogues and the inorganic phosphate-H₂18O exchange reaction. J. Biol. Chem. 245 (1970) 5319–5325. [PMID: 4319238]
3.	Cooper, R.A. and Kornberg, H.L. Net formation of phosphoenolpyruvate from pyruvate by Escherichia coli. Biochim. Biophys. Acta 104 (1965) 618–620. [PMID: 5322808]
4.	Cooper, R.A. and Kornberg, H.L. Phosphoenolpyruvate synthetase. Methods Enzymol. 13 (1969) 309–314.

[EC 2.7.9.2 created 1976]