The Enzyme Database

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Accepted name: chondroitin 6-sulfotransferase
Reaction: 3′-phosphoadenylyl sulfate + chondroitin = adenosine 3′,5′-bisphosphate + chondroitin 6′-sulfate
For diagram of chondroitin biosynthesis (later stages), click here
Glossary: 3′-phosphoadenylyl sulfate = PAPS
Other name(s): chondroitin 6-O-sulfotransferase; 3′-phosphoadenosine 5′-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase; terminal 6-sulfotransferase; 3′-phosphoadenylyl-sulfate:chondroitin 6′-sulfotransferase
Systematic name: 3′-phosphoadenylyl-sulfate:chondroitin 6′-sulfonotransferase
Comments: The sulfation is at the 6-position of N-acetylgalactosamine residues of chondroitin. Not identical with EC chondroitin 4-sulfotransferase.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 37292-93-6
1.  Habuchi, O. and Miyashita, N. Separation and characterization of chondroitin 6-sulfotransferase and chondroitin 4-sulfotransferase from chick embryo cartilage. Biochim. Biophys. Acta 717 (1982) 414–421. [DOI] [PMID: 6957247]
[EC created 1986]

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