The Enzyme Database

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Accepted name: protein-tyrosine sulfotransferase
Reaction: 3′-phosphoadenylyl sulfate + protein tyrosine = adenosine 3′,5′-bisphosphate + protein tyrosine-O-sulfate
Glossary: 3′-phosphoadenylyl sulfate = PAPS
Other name(s): tyrosylprotein sulfotransferase; 3′-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase
Systematic name: 3′-phosphoadenylyl-sulfate:protein-tyrosine O-sulfonotransferase
Comments: The tyrosine residues of some specific proteins of rat pheochromocytoma cells act as acceptors.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 87588-33-8
1.  Lee, R.W.H. and Huttner, W.B. Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase. J. Biol. Chem. 258 (1983) 11326–11334. [PMID: 6577005]
[EC created 1986]

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