The Enzyme Database

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Accepted name: trehalose 2-sulfotransferase
Reaction: 3′-phosphoadenylyl sulfate + α,α-trehalose = adenosine 3′,5′-bisphosphate + 2-O-sulfo-α,α-trehalose
Glossary: 2-O-sulfo-α,α-trehalose = trehalose 2-sulfate = α-D-glucopyranosyl 2-O-sulfo-α-D-glucopyranoside
Other name(s): Stf0 sulfotransferase; 3′-phosphoadenylyl-sulfate:α,α-trehalose 2-sulfotransferase
Systematic name: 3′-phosphoadenylyl-sulfate:α,α-trehalose 2-sulfonotransferase
Comments: The sulfation of trehalose in the bacterium Mycobacterium tuberculosis is required for the biosynthesis of sulfolipid-1.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Mougous, J.D., Petzold, C.J., Senaratne, R.H., Lee, D.H., Akey, D.L., Lin, F.L., Munchel, S.E., Pratt, M.R., Riley, L.W., Leary, J.A., Berger, J.M. and Bertozzi, C.R. Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nat. Struct. Mol. Biol. 11 (2004) 721–729. [DOI] [PMID: 15258569]
2.  Pi, N., Hoang, M.B., Gao, H., Mougous, J.D., Bertozzi, C.R. and Leary, J.A. Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry. Anal. Biochem. 341 (2005) 94–104. [DOI] [PMID: 15866533]
[EC created 2014]

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