| EC |
2.8.3.13 |
| Accepted name: |
succinate—hydroxymethylglutarate CoA-transferase |
| Reaction: |
succinyl-CoA + 3-hydroxy-3-methylglutarate = succinate + (S)-3-hydroxy-3-methylglutaryl-CoA |
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For diagram of mevalonate biosynthesis, click here |
| Other name(s): |
hydroxymethylglutarate coenzyme A-transferase; dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase |
| Systematic name: |
succinyl-CoA:3-hydroxy-3-methylglutarate CoA-transferase |
| Comments: |
Malonyl-CoA can also act as donor, but more slowly. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 80237-90-7 |
| References: |
| 1. |
Deana, R., Rigoni, F., Deana, A.D. and Galzigna, L. Submitochondrial localization and partial purification of the succinyl CoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver. Biochim. Biophys. Acta 662 (1981) 119–124. [DOI] [PMID: 6946836] |
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| [EC 2.8.3.13 created 1984] |
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