ExplorEnz: EC 3.1.1.104

Your query returned 1 entry. Printable version

3.1.1.104

Accepted name:

5-phospho-D-xylono-1,4-lactonase

Reaction:

(1) D-xylono-1,4-lactone 5-phosphate + H₂O = 5-phospho-D-xylonate
(2) L-arabino-1,4-lactone 5-phosphate + H₂O = 5-phospho-L-arabinate

Systematic name:

5-phospho-D-xylono-1,4-lactone hydrolase

Comments:

The enzyme, characterized from Mycoplasma spp., contains a binuclear metal center with two zinc cations. The enzyme is specific for the phosphorylated forms, and is unable to hydrolyse non-phosphorylated 1,4-lactones.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, PDB

References:

Korczynska, M., Xiang, D.F., Zhang, Z., Xu, C., Narindoshvili, T., Kamat, S.S., Williams, H.J., Chang, S.S., Kolb, P., Hillerich, B., Sauder, J.M., Burley, S.K., Almo, S.C., Swaminathan, S., Shoichet, B.K. and Raushel, F.M. Functional annotation and structural characterization of a novel lactonase hydrolyzing D-xylono-1,4-lactone-5-phosphate and L-arabino-1,4-lactone-5-phosphate. Biochemistry 53 (2014) 4727–4738. [PMID: 24955762]

[EC 3.1.1.104 created 2018]