| EC |
3.1.1.120 |
| Accepted name: |
L-fucono-1,5-lactonase |
| Reaction: |
L-fucono-1,5-lactone + H2O = L-fuconate |
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For diagram of L-fucose catabolism, click here |
| Systematic name: |
L-fucono-1,5-lactone lactonohydrolase |
| Comments: |
The enzyme, characterized from the bacterium Burkholderia multivorans, participates in an L-fucose degradation pathway. The enzyme exhibits catalytic activity for the hydrolysis of several lactones, including L-fucono-1,4-lactone, D-arabinono-1,4-lactone, L-xylono-1,4-lactone, and L-galactono-1,4-lactone, but L-fucono-1,5-lactone is the best substrate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Hobbs, M.E., Vetting, M., Williams, H.J., Narindoshvili, T., Kebodeaux, D.M., Hillerich, B., Seidel, R.D., Almo, S.C. and Raushel, F.M. Discovery of an L-fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily. Biochemistry 52 (2013) 239–253. [DOI] [PMID: 23214453] |
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| [EC 3.1.1.120 created 2022] |
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