| EC |
3.1.1.13 |
| Accepted name: |
sterol esterase |
| Reaction: |
a steryl ester + H2O = a sterol + a fatty acid |
| Other name(s): |
cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase |
| Systematic name: |
steryl-ester acylhydrolase |
| Comments: |
A group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. Activated by bile salts. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9026-00-0 |
| References: |
| 1. |
Hyun, J., Kothari, H., Herm, E., Mortenson, J., Treadwell, C.R. and Vahouny, G.V. Purification and properties of pancreatic juice cholesterol esterase. J. Biol. Chem. 244 (1969) 1937–1945. [PMID: 5780846] |
| 2. |
Okawa, Y. and Yamaguchi, T. Studies on sterol-ester hydrolase from Fusarium oxysporum. I. Partial purification and properties. J. Biochem. (Tokyo) 81 (1977) 1209–1215. [PMID: 19426] |
| 3. |
Vahouny, G.V. and Tradwell, C.R. Enzymatic synthesis and hydrolysis of cholesterol esters. Methods Biochem. Anal. 16 (1968) 219–272. [PMID: 4877146] |
| 4. |
Warnaar, F. Triterpene ester synthesis in latex of Euphorbia species. Phytochemistry 26 (1987) 2715–2721. |
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| [EC 3.1.1.13 created 1961, modified 1990] |
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