EC |
3.1.1.28 |
Accepted name: |
acylcarnitine hydrolase |
Reaction: |
O-acylcarnitine + H2O = a fatty acid + L-carnitine |
Other name(s): |
high activity acylcarnitine hydrolase; HACH; carnitine ester hydrolase; palmitoylcarnitine hydrolase; palmitoyl-L-carnitine hydrolase; long-chain acyl-L-carnitine hydrolase; palmitoyl carnitine hydrolase |
Systematic name: |
O-acylcarnitine acylhydrolase |
Comments: |
Acts on higher fatty acid (C6 to C18) esters of L-carnitine; highest activity is with O-decanoyl-L-carnitine. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37278-42-5 |
References: |
1. |
Mahadevan, S. and Sauer, F. Carnitine ester hydrolase of rat liver. J. Biol. Chem. 244 (1969) 4448–4453. [PMID: 5806585] |
2. |
Mentlein, R., Reuter, G. and Heymann, E. Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function. Arch. Biochem. Biophys. 240 (1985) 801–810. [DOI] [PMID: 4026306] |
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[EC 3.1.1.28 created 1972] |
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