| EC |
3.1.1.32 |
| Accepted name: |
phospholipase A1 |
| Reaction: |
phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate |
| Systematic name: |
phosphatidylcholine 1-acylhydrolase |
| Comments: |
This enzyme has a much broader specificity than EC 3.1.1.4 phospholipase A2. Requires Ca2+. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9043-29-2 |
| References: |
| 1. |
Gatt, S. Purification and properties of phospholipase A-1 from rat and calf brain. Biochim. Biophys. Acta 159 (1968) 304–316. [DOI] [PMID: 5657461] |
| 2. |
Scandella, C.J. and Kornberg, A. A membrane-bound phospholipase A1 purified from Escherichia coli. Biochemistry 10 (1971) 4447–4456. [PMID: 4946924] |
| 3. |
van den Bosch, H. Intracellular phospholipases A. Biochim. Biophys. Acta 604 (1980) 191–246. [DOI] [PMID: 6252969] |
| 4. |
van den Bosch, H., Aarsman, A.J. and van Deenen, L.L.M. Isolation and properties of a phospholipase A1 activity from beef pancreas. Biochim. Biophys. Acta 348 (1974) 197–209. [DOI] [PMID: 4858811] |
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| [EC 3.1.1.32 created 1972, modified 1976] |
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