The Enzyme Database

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EC 3.1.1.67     
Accepted name: fatty-acyl-ethyl-ester synthase
Reaction: a long-chain-fatty-acyl ethyl ester + H2O = a long-chain-fatty acid + ethanol
Glossary: a long-chain-fatty acid = a fatty acid with an aliphatic chain of 13-22 carbons.
Other name(s): FAEES
Systematic name: long-chain-fatty-acyl-ethyl-ester acylhydrolase
Comments: The reaction, forms ethyl esters from fatty acids and ethanol in the absence of coenzyme A or ATP. Best substrates are unsaturated octadecanoic acids; palmitate, stearate and arachidonate also act, but more slowly.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 90119-16-7
References:
1.  Mogelson, S. and Lange, L.G. Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthase. Biochemistry 23 (1984) 4075–4081. [PMID: 6487591]
[EC 3.1.1.67 created 1989]
 
 


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