| EC |
3.1.1.8 |
| Accepted name: |
cholinesterase |
| Reaction: |
an acylcholine + H2O = choline + a carboxylate |
| Other name(s): |
pseudocholinesterase; butyrylcholine esterase; non-specific cholinesterase; choline esterase II (unspecific); benzoylcholinesterase; choline esterase; butyrylcholinesterase; propionylcholinesterase; BtChoEase |
| Systematic name: |
acylcholine acylhydrolase |
| Comments: |
Acts on a variety of choline esters and a few other compounds. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9001-08-5 |
| References: |
| 1. |
Augustinsson, K.-B. Cholinesterases. A study in comparative enzymology. Acta Physiol. Scand. 15, Suppl. 2 (1948) . |
| 2. |
Augustinsson, K.-B. and Olsson, B. Esterases in the milk and blood plasma of swine. 1. Substrate specificity and electrophoresis studies. Biochem. J. 71 (1959) 477–484. [PMID: 13638253] |
| 3. |
Koelle, G.B. Cholinesterases of the tissues and sera of rabbits. Biochem. J. 53 (1953) 217–226. [PMID: 13032058] |
| 4. |
Nachmansohn, D. and Wilson, I.B. The enzymic hydrolysis and synthesis of acetylcholine. Adv. Enzymol. Relat. Subj. Biochem. 12 (1951) 259–339. [PMID: 14885021] |
| 5. |
Sawyer, C.H. Hydrolysis of choline esters by liver. Science 101 (1945) 385–386. [PMID: 17780326] |
| 6. |
Strelitz, F. Studies on cholinesterase. 4. Purification of pseudo-cholinesterase from horse serum. Biochem. J. 38 (1944) 86–88. [PMID: 16747753] |
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| [EC 3.1.1.8 created 1961] |
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