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Your query returned 1 entry. 
Printable version
| EC | 3.1.1.93 | ||
| Accepted name: | mycophenolic acid acyl-glucuronide esterase | ||
| Reaction: | mycophenolic acid O-acyl-glucuronide + H2O = mycophenolate + D-glucuronate | ||
| Glossary: | mycophenolate = (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate mycophenolic acid O-acyl-glucuronide = 1-O-[(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoyl]-β-D-glucopyranuronic acid |
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| Other name(s): | mycophenolic acid acyl-glucuronide deglucuronidase; AcMPAG deglucuronidase | ||
| Systematic name: | mycophenolic acid O-acyl-glucuronide-ester hydrolase | ||
| Comments: | This liver enzyme deglucuronidates mycophenolic acid O-acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate that is thought to be immunotoxic. | ||
| Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB | ||
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