The Enzyme Database

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Accepted name: acetoacetyl-CoA hydrolase
Reaction: acetoacetyl-CoA + H2O = CoA + acetoacetate
For diagram of mevalonate biosynthesis, click here
Other name(s): acetoacetyl coenzyme A hydrolase; acetoacetyl CoA deacylase; acetoacetyl coenzyme A deacylase
Systematic name: acetoacetyl-CoA hydrolase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37288-10-1
1.  Aragón, J.J. and Lowenstein, J.M. A survey of enzymes which generate or use acetoacetyl thioesters in rat liver. J. Biol. Chem. 258 (1983) 4725–4733. [PMID: 6131897]
2.  Drummond, G.I. and Stern, J.R. Enzymes of ketone body metabolism. II. Properties of an acetoacetate-synthesizing enzyme prepared from ox liver. J. Biol. Chem. 235 (1960) 318–325. [PMID: 13818236]
[EC created 1972]

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