The Enzyme Database

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Accepted name: S-formylglutathione hydrolase
Reaction: S-formylglutathione + H2O = glutathione + formate
Systematic name: S-formylglutathione hydrolase
Comments: Also hydrolyses S-acetylglutathione, but more slowly.
Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 83380-83-0
1.  Uotila, L. Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases. Biochemistry 12 (1973) 3938–3943. [PMID: 4200890]
2.  Uotila, L. and Koivusalo, M. Purification and properties of S-formylglutathione hydrolase from human liver. J. Biol. Chem. 249 (1974) 7664–7672. [PMID: 4436331]
3.  Harms, N., Ras, J., Reijnders, W.N., van Spanning, R.J. and Stouthamer, A.H. S-Formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification? J. Bacteriol. 178 (1996) 6296–6299. [DOI] [PMID: 8892832]
[EC created 1978]

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