The Enzyme Database

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Accepted name: citrate-lyase deacetylase
Reaction: acetyl-[citrate (pro-3S)-lyase] + H2O = holo-[citrate (pro-3S)-lyase] + acetate
Other name(s): [citrate-(pro-3S)-lyase] thiolesterase; acetyl-S-(acyl-carrier protein) enzyme thioester hydrolase; citrate lyase deacetylase; [citrate-(pro-3S)-lyase](acetyl-form) hydrolase
Systematic name: acetyl-[citrate-(pro-3S)-lyase] hydrolase
Comments: In the proteobacterium Rubrivivax gelatinosus, this enzyme modulates the activity of EC, citrate (pro-3S)-lyase, by converting it from its active acetyl form into its inactive thiol form by removal of its acetyl groups [2]. The activity of citrate-lyase deacetylase is itself inhibited by L-glutamate [2].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 58319-93-0
1.  Giffhorn, F. and Gottschalk, G. Inactivation of citrate lyase from Rhodopseudomonas gelatinosa by a specific deacetylase and inhibition of this inactivation by L-(+)-glutamate. J. Bacteriol. 124 (1975) 1052–1061. [PMID: 356]
2.  Giffhorn, F., Rode, H., Kuhn, A. and Gottschalk, G. Citrate lyase deacetylase of Rhodopseudomonas gelatinosa. Isolation of the enzyme and studies on the inhibition by L-glutamate. Eur. J. Biochem. 111 (1980) 461–471. [DOI] [PMID: 7460909]
[EC created 1989]

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