The Enzyme Database

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EC 3.1.2.25     
Accepted name: phenylacetyl-CoA hydrolase
Reaction: phenylglyoxylyl-CoA + H2O = phenylglyoxylate + CoA
For diagram of phenylacetyl-CoA metabolism, click here
Systematic name: phenylglyoxylyl-CoA hydrolase
Comments: This is the second step in the conversion of phenylacetyl-CoA to phenylglyoxylate, the first step being carried out by EC 1.17.5.1, phenylacetyl-CoA dehydrogenase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 57219-72-4
References:
1.  Rhee, S.K. and Fuchs, G. Phenylacetyl-CoA:acceptor oxidoreductase, a membrane-bound molybdenum-iron-sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica. Eur. J. Biochem. 262 (1999) 507–515. [DOI] [PMID: 10336636]
2.  Schneider, S. and Fuchs, G. Phenylacetyl-CoA:acceptor oxidoreductase, a new α-oxidizing enzyme that produces phenylglyoxylate. Assay, membrane localization, and differential production in Thauera aromatica. Arch. Microbiol. 169 (1998) 509–516. [PMID: 9575237]
[EC 3.1.2.25 created 2004]
 
 


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