| EC |
3.1.22.5 |
| Accepted name: |
deoxyribonuclease X |
| Reaction: |
Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes |
| Other name(s): |
Escherichia coli endodeoxyribonuclease; Escherichia coli endodeoxyribonuclease X |
| Comments: |
Preference for supercoiled DNA; little activity on linear double-stranded DNA. Inhibited by single-stranded DNA, ATP and AMP. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 97002-82-9 |
| References: |
| 1. |
Ghosh, S. and DasGupta, U. Studies with endonuclease X: a new deoxyendonuclease of E. coli that preferentially cleaves supercoiled plasmid DNA. Curr. Trends Life Sci. 12 (1984) 79–88. |
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| [EC 3.1.22.5 created 1992] |
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