The Enzyme Database

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EC 3.1.25.1     
Accepted name: deoxyribonuclease (pyrimidine dimer)
Reaction: Endonucleolytic cleavage near pyrimidine dimers to products with 5′-phosphate
Other name(s): endodeoxyribonuclease (pyrimidine dimer); endodeoxyribonuclease (pyrimidine dimer); bacteriophage T4 endodeoxyribonuclease V; T4 endonuclease V
Comments: Acts on a damaged strand, 5′ from the damaged site.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 66143-22-4
References:
1.  Braun, A.G., Radman, M. and Grossman, L. Enzymic repair of DNA: sites of hydrolysis by the Escherichia coli endonuclease specific for pyrimidine dimers (corendonuclease II). Biochemistry 15 (1976) 4116–4120. [PMID: 786366]
2.  Riazuddin, S. and Grossman, L. Micrococcus luteus correndonucleases. II. Mechanism of action of two endonucleases specific for DNA containing pyrimidine dimers. J. Biol. Chem. 252 (1977) 6287–6293. [PMID: 330526]
[EC 3.1.25.1 created 1978]
 
 


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