| EC |
3.1.26.4 |
| Accepted name: |
ribonuclease H |
| Reaction: |
Endonucleolytic cleavage to 5′-phosphomonoester |
| Other name(s): |
endoribonuclease H (calf thymus); RNase H; RNA*DNA hybrid ribonucleotidohydrolase; hybrid ribonuclease; hybridase; hybridase (ribonuclease H); ribonuclease H; hybrid nuclease; calf thymus ribonuclease H |
| Comments: |
Acts on RNA-DNA hybrids. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9050-76-4 |
| References: |
| 1. |
Haberkern, R.C. and Cantoni, G.L. Studies on a calf thymus ribonuclease specific for ribonucleic acid-deoxyribonucleic acid hybrids. Biochemistry 12 (1973) 2389–2395. [PMID: 4709937] |
| 2. |
Stavrianopoulos, J.G. and Chargaff, E. Purification and properties of ribonuclease H of calf thymus. Proc. Natl. Acad. Sci. USA 70 (1973) 1959–1963. [DOI] [PMID: 4516197] |
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| [EC 3.1.26.4 created 1978, modified 2010] |
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