EC |
3.1.26.5 |
Accepted name: |
ribonuclease P |
Reaction: |
Endonucleolytic cleavage of RNA, removing 5′-extranucleotides from tRNA precursor |
Other name(s): |
RNase P |
Comments: |
An RNA-containing enzyme, essential for tRNA processing; generates 5′-termini or mature tRNA molecules. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
References: |
1. |
Bikoff, E.K. and Gefter, M.L. In vitro synthesis of transfer RNA. I. Purification of required components. J. Biol. Chem. 250 (1975) 6240–6247. [PMID: 1099089] |
2. |
Bikoff, E.K., La Rue, B.F. and Gefter, M.L. In vitro synthesis of transfer RNA. II. Identification of required enzymatic activities. J. Biol. Chem. 250 (1975) 6248–6255. [PMID: 1099090] |
3. |
Robertson, H.D., Altman, S. and Smith, J.D. Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor. J. Biol. Chem. 247 (1972) 5243–5251. [PMID: 4560501] |
|
[EC 3.1.26.5 created 1978, modified 1982] |
|
|
|
|