ExplorEnz: EC 3.1.31.1

Your query returned 1 entry. Printable version

3.1.31.1

Accepted name:

micrococcal nuclease

Reaction:

Endonucleolytic cleavage to nucleoside 3′-phosphates and 3′-phosphooligonucleotide end-products

Other name(s):

spleen endonuclease; thermonuclease; nuclease T; micrococcal endonuclease; nuclease T′; staphylococcal nuclease; spleen phosphodiesterase; Staphylococcus aureus nuclease; Staphylococcus aureus nuclease B; ribonucleate (deoxynucleate) 3′-nucleotidohydrolase

Comments:

Hydrolyses double- or single-stranded substrate.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9013-53-0

References:

1.	Alexander, M., Heppel, L.A. and Hurwitz, J. The purification and properties of micrococcal nuclease. J. Biol. Chem. 236 (1961) 3014–3019. [PMID: 13860347]
2.	Anfinsen, C.B., Cuatrecasas, P. and Taniuchi, H. Staphylococcal nuclease, chemical properties and catalysis. In: Boyer, P.D. (Ed.), The Enzymes, 3rd edn, vol. 4, Academic Press, New York, 1971, pp. 177–204.
3.	Reddi, K.K. Micrococcal nuclease. Methods Enzymol. 12A (1967) 257–262.
4.	Sulkowski, E. and Laskowski, M. , Sr. Phosphatase-free crystalline micrococcal nuclease. J. Biol. Chem. 241 (1966) 4386–4388. [PMID: 5922962]

[EC 3.1.31.1 created 1961 as EC 3.1.4.7, transferred 1978 to EC 3.1.31.1, modified 1981]