| EC |
3.1.6.13 |
| Accepted name: |
iduronate-2-sulfatase |
| Reaction: |
Hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin |
| Other name(s): |
chondroitinsulfatase; idurono-2-sulfatase; iduronide-2-sulfate sulfatase; L-iduronosulfatase; L-idurono sulfate sulfatase; iduronate sulfatase; sulfo-L-iduronate sulfatase; L-iduronate 2-sulfate sulfatase; sulfoiduronate sulfohydrolase; 2-sulfo-L-iduronate 2-sulfatase; iduronate-2-sulfate sulfatase; iduronate sulfate sulfatase |
| Systematic name: |
L-iduronate-2-sulfate 2-sulfohydrolase |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 50936-59-9 |
| References: |
| 1. |
Archer, I.M., Harper, P.S. and Wusteman, F.S. Multiple forms of iduronate 2-sulphate sulphatase in human tissues and body fluids. Biochim. Biophys. Acta 708 (1982) 134–140. [DOI] [PMID: 6816283] |
| 2. |
Bach, J., Eisenberg, F., Cantz, M. and Neufeld, E.C. The defect in the Hunter syndrome: deficiency of sulfoiduronate sulfatase. Proc. Natl. Acad. Sci. USA 70 (1973) 2134–2138. [DOI] [PMID: 4269173] |
| 3. |
DiNatale, P. and Ronsivalle, L. Identification and partial characterization of two enzyme forms of iduronate sulfatase from human placenta. Biochim. Biophys. Acta 661 (1981) 106–111. [DOI] [PMID: 6945876] |
| 4. |
Yutaka, T., Fluharty, A.L., Stevens, R.L. and Kihara, H. Purification and some properties of human liver iduronate sulfatase. J. Biochem. (Tokyo) 91 (1982) 433–441. [PMID: 6950934] |
|
| [EC 3.1.6.13 created 1984] |
| |
|
| |
|
Printable version