| EC |
3.1.6.14 |
| Accepted name: |
N-acetylglucosamine-6-sulfatase |
| Reaction: |
Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate |
| Other name(s): |
chondroitinsulfatase; O,N-disulfate O-sulfohydrolase; acetylglucosamine 6-sulfatase; N-acetylglucosamine 6-sulfate sulfatase; acetylglucosamine 6-sulfatase; 2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase |
| Systematic name: |
N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase |
| Comments: |
May be identical with EC 3.1.6.11 disulfoglucosamine-6-sulfatase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 65666-34-4 |
| References: |
| 1. |
Basner, R., Kresse, H. and von Figura, K. N-Acetylglucosamine-6-sulfate sulfatase from human urine. J. Biol. Chem. 254 (1979) 1151–1158. [PMID: 762121] |
| 2. |
Kresse, H., Fuchs, W., Glössl, J., Holtfrerich, D. and Gilberg, W. Liberation of N-acetylglucosamine-6-sulfate by human β-N-acetylhexosaminidase A. J. Biol. Chem. 256 (1981) 12926–12932. [PMID: 6458607] |
| 3. |
Weissmann, B., Chao, H. and Chow, P. A glucosamine O,N-disulfate O-sulfohydrolase with a probable role in mammalian catabolism of heparan sulfate. Biochem. Biophys. Res. Commun. 97 (1980) 827–833. [DOI] [PMID: 6451222] |
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| [EC 3.1.6.14 created 1984] |
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