EC |
3.13.1.6 |
Accepted name: |
[CysO sulfur-carrier protein]-S-L-cysteine hydrolase |
Reaction: |
[CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + H2O = [CysO sulfur-carrier protein]-Gly-NH-CH2-COOH + L-cysteine |
Other name(s): |
mec (gene name) |
Systematic name: |
[CysO sulfur-carrier protein]-S-L-cysteine sulfohydrolase |
Comments: |
Requires Zn2+. The enzyme, characterized from the bacterium Mycobacterium tuberculosis, participates in an L-cysteine biosynthesis pathway. It acts on the product of EC 2.5.1.113, [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
References: |
1. |
Burns, K.E., Baumgart, S., Dorrestein, P.C., Zhai, H., McLafferty, F.W. and Begley, T.P. Reconstitution of a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. J. Am. Chem. Soc. 127 (2005) 11602–11603. [DOI] [PMID: 16104727] |
|
[EC 3.13.1.6 created 2017] |
|
|
|
|