| EC |
3.2.1.105 |
| Accepted name: |
3α(S)-strictosidine β-glucosidase |
| Reaction: |
strictosidine + H2O = D-glucose + strictosidine aglycone |
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For diagram of geissoschizine and sarpagine biosynthesis, click here |
| Systematic name: |
strictosidine β-D-glucohydrolase |
| Comments: |
Does not act on a number of closely related glycosides. Strictosidine is a precursor of indole alkaloids. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 73379-57-4 |
| References: |
| 1. |
Hemscheidt, T. and Zenk, M.H. Glucosidases involved in indole alkaloid biosynthesis of Catharanthus cell cultures. FEBS Lett. 110 (1980) 187–191. [DOI] [PMID: 6768587] |
| 2. |
Barleben, L., Ma, X., Koepke, J., Peng, G., Michel, H. and Stöckigt, J. Expression, purification, crystallization and preliminary X-ray analysis
of strictosidine glucosidase, an enzyme initiating biosynthetic pathways
to a unique diversity of indole alkaloid skeletons. Biochim. Biophys. Acta 1747 (2005) 89–92. [DOI] [PMID: 15680242] |
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| [EC 3.2.1.105 created 1984] |
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