| EC |
3.2.1.123 |
| Accepted name: |
endoglycosylceramidase |
| Reaction: |
oligoglycosylglucosyl-(1↔1)-ceramide + H2O = ceramide + oligoglycosylglucose |
| Other name(s): |
endoglycoceramidase; EGCase; glycosyl-N-acetyl-sphingosine 1,1-β-D-glucanohydrolase; oligoglycosylglucosylceramide glycohydrolase; oligoglycosylglucosyl(1↔1)ceramide glycohydrolase |
| Systematic name: |
oligoglycosylglucosyl-(1↔1)-ceramide glycohydrolase |
| Comments: |
An enzyme from Rhodococcus sp. that degrades various acidic and neutral glycosphingolipids to oligosaccharides and ceramides, by cleaving a glucosyl bond. Does not act on monoglycosylceramides. cf. EC 3.2.1.62 glycosylceramidase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 105503-61-5 |
| References: |
| 1. |
Ito, M. and Yamagata, T. A novel glycosphingolipid-degrading enzyme cleaves the linkage between the oligosaccharide and ceramide of neutral and acidic glycosphingolipids. J. Biol. Chem. 261 (1986) 14278–14282. [PMID: 3771534] |
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| [EC 3.2.1.123 created 1989] |
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