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Your query returned 1 entry. Printable version
EC | 3.3.2.8 | ||||||
Accepted name: | limonene-1,2-epoxide hydrolase | ||||||
Reaction: | 1,2-epoxymenth-8-ene + H2O = menth-8-ene-1,2-diol | ||||||
For diagram of limonene catabolism, click here | |||||||
Glossary: | limonene = a monoterpenoid limonene-1,2-epoxide = 1,2-epoxymenth-8-ene limonene-1,2-diol = menth-8-ene-1,2-diol |
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Other name(s): | limonene oxide hydrolase | ||||||
Systematic name: | 1,2-epoxymenth-8-ene hydrolase | ||||||
Comments: | Involved in the monoterpene degradation pathway of the actinomycete Rhodococcus erythropolis. The enzyme hydrolyses several alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide. It differs from the previously described epoxide hydrolases [EC 3.3.2.4 (trans-epoxysuccinate hydrolase), EC 3.3.2.6 (leukotriene-A4 hydrolase), EC 3.3.2.7 (hepoxilin-epoxide hydrolase), EC 3.3.2.9 (microsomal epoxide hydrolase) and EC 3.3.2.10 (soluble epoxide hydrolase)] as it is not inhibited by 2-bromo-4′-nitroacetophenone, diethyl dicarbonate, 4-fluorochalcone oxide or 1,10-phenanthroline. Both enantiomers of menth-8-ene-1,2-diol [i.e. (1R,2R,4S)-menth-8-ene-1,2-diol and (1S,2S,4R)-menth-8-ene-1,2-diol] are metabolized. | ||||||
Links to other databases: | BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 216503-88-7 | ||||||
References: |
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