EC |
3.4.19.7 |
Accepted name: |
N-formylmethionyl-peptidase |
Reaction: |
Release of an N-terminal, formyl-methionyl residue from a polypeptide |
Other name(s): |
(fMet)-releasing enzyme; formylmethionine aminopeptidase |
Comments: |
Highly specific for N-formylmethionyl peptides. Will not cleave methionyl peptides or N-formyl derivatives of amino acids other than methionine. Isolated from rat liver. Inhibited by heavy metals and activated by Cl- |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 76106-80-4 |
References: |
1. |
Suda, H., Yamamoto, K., Aoyagi, T. and Umezawa, H. Purification and properties of N-formylmethionine aminopeptidase from rat liver. Biochim. Biophys. Acta 616 (1980) 60–67. [DOI] [PMID: 7437450] |
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[EC 3.4.19.7 created 1992] |
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