The Enzyme Database

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Accepted name: N-formylmethionyl-peptidase
Reaction: Release of an N-terminal, formyl-methionyl residue from a polypeptide
Other name(s): (fMet)-releasing enzyme; formylmethionine aminopeptidase
Comments: Highly specific for N-formylmethionyl peptides. Will not cleave methionyl peptides or N-formyl derivatives of amino acids other than methionine. Isolated from rat liver. Inhibited by heavy metals and activated by Cl-
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 76106-80-4
1.  Suda, H., Yamamoto, K., Aoyagi, T. and Umezawa, H. Purification and properties of N-formylmethionine aminopeptidase from rat liver. Biochim. Biophys. Acta 616 (1980) 60–67. [DOI] [PMID: 7437450]
[EC created 1992]

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