The Enzyme Database

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Accepted name: chymotrypsin C
Reaction: Preferential cleavage: Leu┼, Tyr┼, Phe┼, Met┼, Trp┼, Gln┼, Asn┼
Comments: Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 9036-09-3
1.  Peanasky, R.J., Gratecos, D., Baratti, J. and Rovery, M. Mode of activation and N-terminal sequence of subunit II in bovine procarboxypeptidase A and of porcine chymotrypsinogen C. Biochim. Biophys. Acta 181 (1969) 82–92. [DOI] [PMID: 5792601]
2.  Folk, J.E. Chymotrypsin C (porcine pancreas). Methods Enzymol. 19 (1970) 109–112.
3.  Wilcox, P.E. Chymotrypsinogens - chymotrypsins. Methods Enzymol. 19 (1970) 64–108.
[EC created 1972]

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