| EC |
3.4.21.69 |
| Accepted name: |
protein C (activated) |
| Reaction: |
Degradation of blood coagulation factors Va and VIIIa |
| Other name(s): |
blood-coagulation factor XIVa; activated blood coagulation factor XIV; activated protein C; autoprothrombin II-A; protein Ca; APC; GSAPC |
| Comments: |
A peptidase of family S1 (trypsin family), one of the γ-carboxyglutamic acid-containing coagulation factors. Formed from protein C, the proenzyme that circulates in plasma, by the action of a complex of thrombin with thrombomodulin, or by serine endopeptidases present in several snake venoms |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 42617-41-4 |
| References: |
| 1. |
Esmon, C.T. The regulation of natural anticoagulant pathways. Science 235 (1987) 1348–1352. [DOI] [PMID: 3029867] |
| 2. |
Esmon, C.T. The roles of protein C and thrombomodulin in the regulation of blood coagulation. J. Biol. Chem. 264 (1989) 4743–4746. [PMID: 2538457] |
|
| [EC 3.4.21.69 created 1992] |
| |
|
| |
|
Printable version