The Enzyme Database

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EC 3.4.21.7     
Accepted name: plasmin
Reaction: Preferential cleavage: Lys┼ > Arg┼
higher selectivity than trypsin. Converts fibrin into soluble products
Other name(s): fibrinase; fibrinolysin; actase; serum tryptase; thrombolysin
Comments: Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. In peptidase family S1 (trypsin family).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 9001-90-5
References:
1.  Castellino, F.J. and Sodetz, J.M. Rabbit plasminogen and plasmin isozymes. Methods Enzymol. 45 (1976) 273–286. [DOI] [PMID: 138065]
2.  Castellino, F.J. and Powell, J.R. Human plasminogen. Methods Enzymol. 80 (1981) 365–378. [PMID: 6210827]
3.  Robbins, K.C., Summaria, L. and Wohl, R.C. Human plasmin. Methods Enzymol. 80 (1981) 379–387. [PMID: 6210828]
[EC 3.4.21.7 created 1961 as EC 3.4.4.14, transferred 1972 to EC 3.4.21.7]
 
 


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