| EC |
3.4.22.51 |
| Accepted name: |
cruzipain |
| Reaction: |
Broad endopeptidase specificity similar to that of cathepsin L |
| Other name(s): |
congopain; cruzain; evansain; trypanopain |
| Comments: |
In peptidase family C1. Is located in the digestive vacuoles of the parasitic trypanosome and contributes to the nutrition of the organism by digestion of host proteins. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 141588-22-9 |
| References: |
| 1. |
Cazzulo, J.J., Stoka, V. and Turk, V. The major cysteine proteinase of Trypanosoma cruzi: a valid target for chemotherapy of Chagas disease. Curr. Pharm. Des. 7 (2001) 1143–1156. [PMID: 11472258] |
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| [EC 3.4.22.51 created 2003] |
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