| EC |
3.4.24.12 |
| Accepted name: |
envelysin |
| Reaction: |
Hydrolysis of proteins of the fertilization envelope and dimethylcasein |
| Other name(s): |
sea-urchin-hatching proteinase; hatching enzyme; chorionase; chorion-digesting proteinase; chymostrypsin; sea urchin embryo hatching enzyme |
| Comments: |
A glycoprotein from various members of the class Echinoidea. Extracellular enzyme requiring Ca2+. In peptidase family M10 (interstitial collagenase family) |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 50812-13-0 |
| References: |
| 1. |
Barrett, D. and Edwards, B.F. Hatching enzyme of the sea urchin Strongylocentrotus purpuratus. Methods Enzymol. 45 (1976) 354–373. [DOI] [PMID: 1012003] |
| 2. |
Lepage, T. and Gache, C. Purification and characterization of the sea urchin embryo hatching enzyme. J. Biol. Chem. 264 (1989) 4787–4793. [PMID: 2925668] |
| 3. |
Lepage, T. and Gache, C. Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo. EMBO J. 9 (1990) 3003–3012. [PMID: 2167841] |
| 4. |
Nomura, K., Tanaka, H., Kikkawa, Y., Yamaguchi, M. and Suzuki, N. The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family. Biochemistry 30 (1991) 6115–6123. [PMID: 1711895] |
|
| [EC 3.4.24.12 created 1978] |
| |
|
| |
|
Printable version