| EC |
3.4.24.50 |
| Accepted name: |
bothrolysin |
| Reaction: |
Cleavage of Gln4┼His, Ser9┼His and Ala14┼Leu of insulin B chain and Pro┼Phe of angiotensin I |
| Other name(s): |
Bothrops metalloendopeptidase J; J protease |
| Comments: |
A 22.5 kDa endopeptidase from the venom of the jararaca snake (Bothrops jararaca), insensitive to phosphoramidon at 0.5 mM. In peptidase family M12 (astacin family) |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 443890-65-1 |
| References: |
| 1. |
Tanizaki, M.M., Zingali, R.B., Kawazaki, H., Imajoh, S., Yamazaki, S. and Suzuki, K. Purification and some characteristics of a zinc metalloprotease from the venom of Bothrops jararaca (jararaca). Toxicon 27 (1989) 747–755. [PMID: 2781574] |
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| [EC 3.4.24.50 created 1992] |
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