| EC |
3.4.24.53 |
| Accepted name: |
trimerelysin II |
| Reaction: |
Cleavage of Asn3┼Gln, His10┼Leu and Ala14┼Leu in the insulin B chain, and the bond Z-Gly-Pro┼Leu-Gly-Pro in a small molecule substrate of microbial collagenase |
| Other name(s): |
Trimeresurus metalloendopeptidase II; proteinase H2; H2-proteinase |
| Comments: |
A 24 kDa nonhemorrhagic endopeptidase from the venom of the habu snake (Trimeresurus flavoviridis). In peptidase family M12 (astacin family) |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 151125-15-4 |
| References: |
| 1. |
Takahashi, T. and Ohsaka, A. Purification and characterization of a proteinase in the venom of Trimeresurus flavoviridis. Complete separation of the enzyme from hemorrhagic activity. Biochim. Biophys. Acta 198 (1970) 293–307. [DOI] [PMID: 4984550] |
| 2. |
Takeya, H., Arakawa, M., Miyata, T., Iwanaga, S. and Omori-Satoh, T. Primary structure of H2-proteinase, a non-hemorrhagic metalloproteinase, isolated from the venom of the habu snake, Trimeresurus flavoviridis. J. Biochem. (Tokyo) 106 (1989) 151–157. [PMID: 2777746] |
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| [EC 3.4.24.53 created 1992] |
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