EC |
3.4.24.6 |
Accepted name: |
leucolysin |
Reaction: |
Cleavage of Phe1┼Val, His5┼Leu, Ala14┼Leu, Gly20┼Glu, Gly23┼Phe and Phe24┼Phe bonds in insulin B chain as well as N-blocked dipeptides |
Other name(s): |
Leucostoma neutral proteinase; Leucostoma peptidase A |
Comments: |
From the venom of the western cottonmouth moccasin snake (Agkistrodon piscivorus leucostoma). |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 72561-03-6 |
References: |
1. |
Wagner, F.W., Spiekerman, A.M. and Prescott, J.M. Leucostoma peptidase A. Isolation and physical properties. J. Biol. Chem. 243 (1968) 4486–4493. [PMID: 5684005] |
2. |
Spiekerman, A.M., Fredericks, K.K., Wagner, F.W. and Prescott, J.M. Leucostoma peptidase A: a metalloprotease from snake venom. Biochim. Biophys. Acta 293 (1973) 464–475. [DOI] [PMID: 4711816] |
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[EC 3.4.24.6 created 1978] |
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