The Enzyme Database

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Accepted name: gpr endopeptidase
Reaction: Endopeptidase action with P4 Glu or Asp, P1 preferably Glu Asp, P1′ hydrophobic and P2′ Ala
Other name(s): germination proteinase
Comments: Initiates the degradation of small, acid-soluble proteins during spore germination in Bacillus megaterium. Type example of peptidase family A25.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 75718-32-0
1.  Ponnuraj, K., Rowland, S., Nessi, C., Setlow, P. and Jedrzejas, M.J. Crystal structure of a novel germination protease from spores of Bacillus megaterium: Structural arrangement and zymogen activation. J. Mol. Biol. 300 (2000) 1–10. [DOI] [PMID: 10864493]
[EC created 2003]

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