The Enzyme Database

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Accepted name: asparaginase
Reaction: L-asparagine + H2O = L-aspartate + NH3
Other name(s): asparaginase II; L-asparaginase; colaspase; elspar; leunase; crasnitin; α-asparaginase
Systematic name: L-asparagine amidohydrolase
Links to other databases: BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9015-68-3
1.  Halpern, Y.S. and Grossowicz, N. Hydrolysis of amides by extracts from mycobacteria. Biochem. J. 65 (1957) 716–720. [PMID: 13426090]
2.  Ho, P.P.K., Frank, B.H. and Burck, P.J. Crystalline L-asparaginase from Escherichia coli B. Science 165 (1969) 510–512. [DOI] [PMID: 4894591]
3.  Suld, H.M. and Herbut, P.A. Guinea pig serum and liver L-asparaginases. Comparison of serum and papain-digested liver L-asparaginases. J. Biol. Chem. 245 (1970) 2797–2801. [PMID: 4987975]
[EC created 1961]

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