| EC |
3.5.1.111 |
| Accepted name: |
2-oxoglutaramate amidase |
| Reaction: |
2-oxoglutaramate + H2O = 2-oxoglutarate + NH3 |
| Glossary: |
2-oxoglutaramate = 2-ketoglutaramate = 5-amino-2,5-dioxopentanoate |
| Other name(s): |
ω-amidase (ambiguous) |
| Systematic name: |
5-amino-2,5-dioxopentanoate amidohydrolase |
| Comments: |
The enzyme, which is highly specific for its substrate, participates in the nicotine degradation pathway of several Gram-positive bacteria. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
| References: |
| 1. |
Cobzaru, C., Ganas, P., Mihasan, M., Schleberger, P. and Brandsch, R. Homologous gene clusters of nicotine catabolism, including a new ω-amidase for α-ketoglutaramate, in species of three genera of Gram-positive bacteria. Res. Microbiol. 162 (2011) 285–291. [DOI] [PMID: 21288482] |
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| [EC 3.5.1.111 created 2012] |
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