| EC |
3.5.1.23 |
| Accepted name: |
ceramidase |
| Reaction: |
a ceramide + H2O = a carboxylate + sphingosine |
| Glossary: |
a ceramide = an N-acylsphingosine |
| Other name(s): |
acylsphingosine deacylase; glycosphingolipid ceramide deacylase |
| Systematic name: |
N-acylsphingosine amidohydrolase |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37289-06-8 |
| References: |
| 1. |
Nilsson, A. The presence of spingomyelin- and ceramide-cleaving enzymes in the small intestinal tract. Biochim. Biophys. Acta 176 (1969) 339–347. [DOI] [PMID: 5775951] |
| 2. |
Yavin, E. and Gatt, S. Enzymatic hydrolysis of sphingolipids. 8. Further purification and properties of rat brain ceramidase. Biochemistry 8 (1969) 1692–1698. [PMID: 5805303] |
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| [EC 3.5.1.23 created 1972, modified 1990] |
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